What they never told you about how your gallbladder works (and what it does to your health after surgery)

What they never told you about how your gallbladder works (and what it does to your health after surgery)

This basic principle  applies to any surgery , albeit different organ systems are affected, but for our purposes, we will relate this to gallbladder surgery (cholecystectomy).

 

ANY time you have surgery (of any sort) you can experience fatigue. Your body only heals when you are asleep – so that is nature’s way of getting you to slow down – so you can heal efficiently [while sleeping]. That said, most people didn’t go into surgery with a fully functioning gallbladder. It could have been dysfunctional or essentially non-functioning for months or even years before that. So , that means you have months or years of digestive issues and not getting the building blocks your body needs to make hormones or repair itself. Surgery brings its own issues, as it increases the demand you have for certain nutrients – like vitamin C, B vitamins, protein, glutathione, etc . So, when you have gallbladder surgery – you go from just being deficient in the fat soluble vitamins (A,D,E,K) and essential fatty acids to being potentially deficient in most of the major vitamin categories. To compound matters, they typically put you on a significant dose of antibiotics after your surgery – which kills off the good bacteria in your gut along with the bad, and since 80% of you immune function comes from the gut and those good bacteria, your immune function goes down , making your MORE tired and susceptible to catching everything that goes around. It is a hard thing to dig yourself out of. You have to overhaul your diet (and you rarely get that advice), you have to get optimal levels of sleep, and you have to get out in the sunshine and fresh air and get some exercise. Otherwise you feel like you are trying to dig yourself out of a hole with a plastic spoon. Now, occasionally people feel great after surgery, but they are the exception to the rule.  In 12 years of practice, I have rarely met anyone who didn’t have to make changes to feel better afterwards. Sooner or later their underlying nutritional deficiencies caught up to them and affected their health.

Miranda

Your body uses cholesterol and vitamin D  as precursors to make many of your hormones, including your sex hormones.  Fats are necessary for life, and your brain is largely a fatty organ.  This is why people taking anti-cholesterol medications (statins) frequently experience decreased libido, or even sexual dysfunction.   They also often experience short term memory issues. statins

I have heard doctors argue that the gallbladder is unnecessary.  They  say that since the liver continues to make bile, then fat absorption continues.   I disagree with this.  First, I don’t believe we were designed with unnecessary parts.  We may not realize their full worth or function yet, but that is a human limitation, not a limitation of our creation.  Science only ‘discovered’ what the appendix was for within the past few years (It acts as a reservoir for healthy bacteria to recolonize our intestines after fever or illness).  Since cholecystectomy is one of the most commonly performed surgical procedures in this country, it makes sense that there is more money in removing them than figuring out how to save them.  But I digress, let’s get back to the liver making bile – it does keep making it.  The level it makes it is dependent on whether you have fatty liver degeneration or not.  But let’s say that you don’t have fatty liver — the liver is going to drip, drip, drip 27-34 oz  bile out in a steady stream.  That bile is very caustic, and would normally be funneled over to the gallbladder where it is collected and concentrated, up to 18 times – down to 1-3 oz.  It is this highly concentrated bile that is designed to break down the fatty acids and fat soluble vitamins you consume.  The pre-concentrated bile, while caustic and irritating to your gastric mucosa, can’t hold a candle to the concentrated bile your gallbladder should hold.   There is never enough, and never enough at the specific concentration required to absorb those key nutrients out of your diet.  So you become deficient and your body goes into conservation mode.  Some experience this immediately, others find it takes 6-24 months to fully start experiencing the effects.  People find it harder and harder to lose weight, or they find themselves gaining weight despite eating the same diet they always did, or exercising.  They find they get fatigued easier, and that they are more susceptible to colds and flu.  If they have autoimmune disorders, they may find themselves experiencing a greater degree of symptoms.

So what can you do?  I will be the first to admit that I don’t have all of the answers.  If anyone suggest that they do – RUN!  I can tell you that what my research, and my experience has led me to works for most people.   First, you need to keep a food journal and track every meal you eat and how you feel afterwards.  Gas, bloating, and diarrhea are the most commonly experienced repercussions from having cholecystectomy.   1 in 15 people who have had their gallbladder removed experience Habba Syndrome, which is commonly misdiagnosed as IBS, or even Celiac Disease.  5-40% of cholecystectomy patients will experience post-cholecystectomy syndrome  (persistent right upper quadrant abdominal pain, bloating, gas, nausea, diarrhea, and general malaise).  Often, these people will know the whereabouts of every bathroom in their vicinity, because they experience issues almost immediately after eating.  Dietary changes will be necessary.  Certain foods aggravate a significant number of people with no gallbladder.  These include greasy foods, carbonated beverages, dairy, and simple carbohydrates.  Wheat products, including breads and beer, can also elicit a negative response.  Please don’t take this as a reason to stop eating healthy fats — you NEED to consume them in order to maintain your health and shift your waistline.  Use specific dietary supplementation to replace some of the action of the gallbladder.  I recommend a blend of ox bile, beet concentrate and pancrelipase to substitute for this action.  If you avoid fats, you will make matters worse.  Since digestive enzyme production decreases with age, if you are over 40, adding digestive enzymes to your meals can also cause significant relief.   make sure you are getting adequate levels of sleep so that your body can repair itself and so that levels of stress hormones can decrease.

  1. Keep a food journal to log your physical responses to foods and beverages. Learn what your body can and cannot handle.
  2. Use specific dietary supplements to increase your digestion and resolve your underlying nutritional deficiencies.
  3. Get 7+ hours of uninterrupted sleep per night.
  4. Get out there and move. Aerobic activity and weight bearing exercise is crucial for your recovery.  Walking is a great way to get started.  Walking in the sunshine is even better (get some vitamin D while you are at it!)

 

Image courtesy of Ohmega1982 at FreeDigitalPhotos.net
By popular request – The *UPDATED* Plateau Buster Protocol!

By popular request – The *UPDATED* Plateau Buster Protocol!

My Plateau Busting protocol is a work in progress, as we discover new information in the literature – we tweak things accordingly.  By popular demand, I have enclosed the updated protocol  here so people can refer to it, but please know that this protocol is the “Cliff Notes” version, and the full program will be outlined in detail in my upcoming book.

One of my most popular videos on Youtube is “What To Do When You Hit a Weight Loss Plateau”, and due to it, and the popularity of my Facebook group  www.facebook.com/WeightLossResources,  I hear from many women from around the country (and around the world) that are immensely frustrated with their inability to lose weight.  Often these women are seemingly doing everything right – they are eating a decent diet, they are exercising, they are making a concerted effort to live healthier  – unfortunately, their bodies are rebelling, and eschewing all of their efforts to shed the pounds.  This is disheartening and demoralizing, and it creates a vicious cycle of trying the next new diet, failing, getting bigger, trying the next new diet, failing etc.

I want to make it clear – you are not a failure!  There is so much erroneous and misinformation in the diet world – you can’t help but be confused.  Furthermore, not every diet is a good match for every person.  Some people are able to thrive on a vegetarian diet, others fail miserably as their quest to avoid meat brings a plethora of low quality processed foods into their diet.  There is always a HUGE difference between how a diet looks on paper and how it is brought to live in a real world setting.  So let me say this; weight loss is never linear.  It always comes off in stair steps.  Our goal is to minimize those stair treads and maximize the risers!  I would love to equip you with simple, easy to implement tools which empower you to make lifestyle changes that result in a happier, healthier YOU!

First off, let’s throw the notion out the door that everyone needs to be a size 2.  It isn’t reasonable, it isn’t healthy, it isn’t practical.  Maybe you have always struggled with your weight, maybe the hormone changes from multiple pregnancies put you on your current course, maybe you have other underlying health challenges… when you set your goal weight, don’t pick one from a statistician’s magic graph, pick one that is reasonable and doable for you!  Make the first step in setting yourself up for success!

 

So, I am going to outline the key steps in helping you blast through those plateaus in 7 simple steps:

  1. Protein for Breakfast!  Our aim is to follow a ketogenic/”Death to Diabetes®”/ Paleo style breakfast.  Your ideal breakfast will be a ‘bulletproof’ coffee (coffee containing a spoonful of melted grass-fed butter and/or coconut oil), at least 35 grams of high quality protein (eggs, meat, fish), and unlimited steamed vegetables (if so desired).  Keep your carbohydrates, yogurts, smoothies, etc for later in the day.
  2.  Snacking  – If you must snack between meals – limit your snacks to protein, or 1-2 oz of healthy seeds or nuts.  When you snack on fruit, dairy, or carbohydrates – you create a bigger spike in your blood glucose levels (and subsequently your insulin), which lends you towards eating more and being hungrier.  It also stimulates you to release hormones which make weight loss more difficult.
  3. Inflammation – reducing your systemic load of inflammation is KEY to getting the pounds off permanently.  You can do this by ensuring that you are getting at least 8 hours of uninterrupted sleep per night.  Getting your carbohydrates from vegetables and fruits as opposed to pastas, breads, and sweets will also help.  Supplements including fish oil, turmeric, boswellia, ginger, or proteolytic enzyme blends will go a long way to reduce your total inflammatory load.  Intenzyme Forte from Biotics Research is one proteolytic enzyme blend that I frequently use with my patients and clients.
  4. Tea time – instead of loading up on sodas, make a concerted effort to drink tea ( hot or cold work equally well) – at least twice a day.  Make a point however to mix up the types of tea that you drink so that you do not consume too much of any particular nutrient that may be found in certain teas (such as fluoride in green tea) .  Black tea, white tea, green tea, roobios tea, dandelion tea, yarrow, rosehip, cornsilk, pu-ehr, matcha, and ginger all have known anti-inflammatory and diuretic properties.  Lemon water or lime water will also work, and they have the added benefit of containing bioflavonoids – which also aid in the process.  TruVision’s Heart & Hydration is another acceptable substitute for any of your  daily cups of tea.
  5. Protein centered meals – While nutritionists vary on what they consider to be the ‘ideal’ daily intake of protein, I find it a good rule of thumb to use HALF OF YOUR IDEAL WEIGHT (LBS)  IN GRAMS (PRO) , so if you currently weigh 225 lbs, but your goal weight is 150 lbs, you need to take 150 divided by 2 = 75.  Therefore, you should strive to consume at least 75 grams of high quality protein per day.  I tell my clients to quit worrying about counting calories, and count grams of protein instead!
  6. Probiotics before bed – more and more studies are demonstrating that gut bacteria play a definitive role in whether you carry extra pounds.  Obese people and average weight people have very different ratios of gut bacteria.  Take 1-2 capsules of a probiotic from my approved list before bedtime, and rotate brands so that you can introduce multiple strains into your gastrointestinal tract.
  7. Move IT or Lose IT – You don’t need to take up decathlons or bench press 300 pounds, but you need to move those joints.  Chiropractors are always fond of the saying “move it or lose it”, and that plays true with your joints and your muscles.  Get out and walk, and if you can’t walk – get a stationary bike.  Most thrift stores have a ton of stationary bikes for just a few dollars!  Your quadriceps are the largest lymphatic pump in your body, you need to start working those on a regular basis and you will flush away the metabolites from breaking down fat.

Want to kickstart the weight loss process?

8.  The TruCombo’s  (TruFix/TruWeight&Energy, both Gen 1 and Gen2)  are one of my secret weight loss weapons.  They both help reduce your appetite, make you feel full quicker, balance glucose fluctuations, reduce cravings, and increase your metabolism.  The cornerstone of either  combo is TruFix, and it is a body balancing supplement. An imbalanced body stores fat, a balanced body will release fat!  TruVision can be an incredible tool in your arsenal to decrease those cravings that make it so hard for you to stick to a program.  It is literally “willpower in a box!”

 plateauA

So now you know the basic steps, but you need to understand the science and rationale behind the recommendations:

 

Rationale 1 : The breakfast needs to be essentially carb-free. Do not ask me if you can have fruit, or yogurt, or cereal, or pancakes, or donuts, or oatmeal, or cheese, or anything else. We want ONLY protein so we are starting off the day by leveling glucose and insulin. Those other foods, even if they are ‘healthy’ choices, will spike your glucose and insulin, and then your TruFix has to work twice as hard to be effective. This is, in effect, a ketogenic or paleo-style breakfast. This type of meal “shifts the body’s metabolic engine from burning carbohydrates to burning fats”2 and improves insulin sensitivity and leptin resistance3. Consuming carbohydrates, even in healthy forms such as those from fruit (fructose) or dairy (lactose) causes surges in blood glucose levels which in turn initiate the release of insulin. People with excess weight have been shown to be insulin resistant4 and therefore if we by pass this, we set the stage for less severe glucose and insulin fluctuations throughout the day. In fact, in his book Death to Diabetes™, researcher DeWayne McCauley postulates that eating a paleo or ketogenic breakfast is the most important factor in modulating glucose levels throughout the day.5  If protein alone doesn’t fill you up, feel free to add 2 cups of any steamed  green vegetable.  You can season it with olive oil, vinegar, and Mrs. Dash seasoning.

Rationale 2 : Snacking should not stimulate the appetite, spike glucose levels, raise leptin levels, or be a major source of calories.  Most people grossly underestimate how many calories are contained in their daily ‘snacks’ and instead of being 100-200 calorie tide-me-overs, snacks have become 700 calorie crappucino’s, milkshakes, yogurt-covered extravaganzas.  If you stop drinking your calories, it is much easier to stick to your daily dietary recommendations.

Rationale 3 :   Where do we start? There are so many! First, let’s take a look at how inflammation makes you fat : Inflammation begins within the fat cells themselves. Most people think of inflammation and assume that means joint pain, but inflammation is so much more. At its very core a fat cell is an inflamed cell. “As glucose is moved into fat cells, they produce an excess of Reactive Oxygen Species (ROS) which in turn initiates an inflammatory cascade within the cell”7. As the percentage of body fat increases, the rate of inflammation increases exponentially. This inflammation causes insulin resistance, and can be noted with C-Reactive Protein testing. The inflammatory cascade eventually makes its way to the brain, specifically the hypothalamus, where it causes leptin resistance.8 Leptin is your ‘hunger’ hormone and is noted for controlling your appetite and regulating your metabolism. The more fat you have the greater potential you have for leptin resistance, which affects your glucose regulation, and slows your metabolism which results in more weight gain and insulin resistance. It is a vicious cycle that keeps getting progressively worse. Inflammation within the gut itself, where 80% of immune function resides, further causes both leptin and insulin resistance. An imbalance in the gram-negative bacteria in the gut has been shown to produce an endotoxin called lipopolysaccharide (LPS) and a cytokine cascade which causes inflammation, insulin resistance, and weight gain.9 But I digress, we will get into how bacteria are related to obesity in the step 6. Obesity makes fat cells act like they are infected.10 The stimulation of fat cells by excess calories causes the cells to make Major Histocompatibility Complex II (MHCII), which in turn sends your immune system into over-drive, mimicking autoimmune dysfunction.11 This breakthrough in understanding the fat cell may prove to be crucial future weight loss and aging studies.

Intenzyme Forte™ is a proteolytic enzyme formula. When taken on an empty stomach, it can be absorbed intact into the bloodstream12 where it can be directed towards breaking down those inflammatory products in the body. Proteolytic enzymes have been demonstrated to reduce Tumor Necrosis Factor alpha (TNF-a), a cytokine protein that signals inflammatory responses along with other pro-inflammatory mediators such as Prostaglandin E2 and Thromboxanes.13 Autoimmune dysfunction is associated with increased levels of TNF-a.14

In addition to the overwhelming capacity of proteolytic enzymes to interrupt this fat-inflammation cycle, certain ones, including bromelain, have a secondary action of helping the body to utilize insulin more efficiently which in turn helps to keep blood glucose fluctuations less dramatic. 15

To summarize all of this technical jargon : fat cells are inflamed cells. Think of each fat cell like a little water balloon filled with fat. The fat creates chemicals which not only irritate the body, but stimulate the body to keep making more and more fat cells. This is very stressful on the body which finds the inflammatory chemicals hugely irritating, so the body tries to dilute those irritants by sending more water to the area (bloating and swelling) to flush those chemicals away. This not only sends the body down the pathway to blood sugar dysregulation and even diabetes, but can result in premature aging and even autoimmune-type degeneration. Once you have made a fat cell, you can never get rid of them (barring surgery like liposuction) but you can deflate those ‘balloons’ of fat, and turn off the inflammation production. That is what we are trying to achieve with this step.

Mid-morning and mid-afternoon take Intenzyme Forte™ .  The protocol recommends 1-2 capsule(s)  of  Intenzyme Forte  mid-morning, and 1-2 capsules mid-afternoon on an empty stomach. Empty stomach usually means 30 minutes+ prior to eating or a minimum of 90 minutes after eating. *This HAS to be taken on an empty stomach or IT WILL NOT WORK!  Please note, if you have significant levels of inflammation, you can take additional capsules twice a day, but for simplicity and to curtail costs,  I suggest starting with 1 capsule twice daily.

If you choose to use one of the other anti inflammatory supplements that are listed above, then change the dosing accordingly.

Rationale 4 : All of these teas have a known mild diuretic effect and by keeping them in rotation our body will not accommodate to it- thereby it maintains its effectiveness. As we already discussed, the body likes to flood inflamed tissues with excess water, so if we drink tea, it’s mild, natural diuretic properties help us flush those inflammatory by-products from the body, and that will support healthy weight loss. Please note: many of the teas listed, particularly the herbal teas are naturally caffeine-free. Should you choose to use green tea or black tea however, it is the caffeine portion of it which acts like a diuretic, so make sure to purchase regular versions and not decaffeinated ones.

Rationale 5 :  Protein intake speeds metabolic rate.  You need to be consuming enough high quality protein in order to trigger your body to release the fat that it has accumulated.  Dieters that fail to consume enough protein will get muscle wasting – so it is in your best interest to make sure that you are consuming enough high quality, non-soy protein.

Rationale 6 :  An increasing body of evidence suggests that obesity is directly linked to the bacteria in your gut. In fact the bacteria in thin people differs from the bacteria in overweight people. 16 Thin people and overweight people have entirely different strains and ratios of intestinal flora.17 Researchers at Laval University in Canada, found that female test subjects receiving probiotics lost twice as many pounds as those in the placebo group over the course of a twelve week period.18 Furthermore, probiotics may normalize intestinal pH, making it more difficult for candida albicans to thrive, and may crowd out pathogenic bacteria species.19 There are variations of professional opinion on the best way to consume probiotics, but heat and acid are enemies of bacteria, so if you can get the probiotics through the stomach acid as quickly as possible, then you have created optimal conditions for the greatest number of probiotics to survive. Hence the need to take them on an empty stomach. Taking them at night coincides with the greatest period of bowel rest for most individuals, which allows for longer periods of contact between the probiotics and the intestinal mucosa, which may improve the rate of colonization. When you take probiotics with food, they stay in the acidic stomach for much longer, which kills off a greater percentage of the bacteria.  Again you want to take your probiotics on an empty stomach so it gets passed through your stomach acid quickly and so it can colonize in your large intestine while you have your longest period of bowel rest. If you take magnesium, this is an ideal time to take it too.

Rationale 7 :  You can not out-exercise a bad diet, and similarly, a clean diet alone will not compensate for a deficit of physical activity.  After  blood, lymph is the largest fluid which circulates in the body and it is very important to maintaining overall health.  Walking is the #1 exercise to encourage lymphatic flow, and moderate to fast paced walking is excellent aerobic activity.  It is a lifestyle modification that is easy to implement and that provides both immediate and long-term benefits.

Rationale  8 :  There are several. First, we want to regulate glucose and insulin spikes.  Even as little of five extra pounds of body weight indicates some degree of insulin resistance.  One, we are consuming the TruFix  at  or near the same time as protein. Protein takes longer to digest than carbohydrates and the stomach retains protein containing meals for longer periods of time before it is sent through to the small intestine. This enhances absorption of the TruFix ingredients.   Two, for those drinking tea or drinking the TruHeart & Hydration drink mix,  there is a well established neural-lingual connection between your taste buds and the brain. Primary gustatory fibers synapse centrally in the medulla, so upon consuming sweet substances, the sweet taste receptors in the mouth stimulates the release of dopamine in the brain. We can use this signaling to turn down the body’s desire for carbohydrate-rich or sweet substances; “…sweet taste is modified by circulating hormones. Recently, the effect of leptin on sweet-responding taste cells has generated much interest. Leptin, a protein hormone secreted mainly by adipocytes regulates body mass and suppresses insulin secretion by the activation of ATP-sensitive KCn . Its inhibitory effect on TRCs also involves the activation of a K+ conductance and membrane hyper polarization. Thereby the hormone partially blunts nerve signals indicating sweet taste, which, presumably, makes food less attractive.”6   If you hold the sweetened (stevia) tea or Heart & Hydration mix in the mouth for several seconds before swallowing it extends the contact time between the taste buds and the sweet taste – thus fooling the brain  into believing that it has consumed a significant amount of carbohydrates, which results in a down regulation of your appetite and sweet cravings.

Other Helpful Pointers: 

  • Meals – Make healthy choices when you can. If you can eat lower amounts of carbohydrates, you should see results faster. Try to eat GOD made foods and avoid as many Man-made foods as possible. *Perfect meals are meat & veggies*
  • If you drink alcohol, limit yourself to one (1) oz of hard liquor or 1 6(oz) glass of wine per day. If you drink more than this, it increases the difficulty you will have losing weight tremendously.
  • Avoid artificial sweeteners
  • Keep your fruits and yogurts as side dishes to your meals – like dessert.
  • If you are having a smoothie – have it with lunch or dinner.
  • If you already exercise, keep continuing what you are doing. Please don’t start a new program at the same time you initiate a new diet. You want to know what is working for you and what isn’t.
  • If you are consuming the beverages as described, please make sure that you are drinking your water. These cups of tea do count towards your daily quota.
  • Please do not skip meals.

Troubleshooting for SPECIAL CASES: 

1) Autoimmune patients have difficulty losing weight.  They usually have elevated levels of inflammation and hormonal imbalances – both of which impact fat burning.  Before starting any diet program, it behooves you to see your physician and get a complete blood workup.  C-Reactive protein  and Thyroid panels are well worth getting.  If you are symptomatic for any autoimmune condition, now is the perfect time to have your endocrinologist review and balance your medications.  I will explore more options for autoimmune patients in future blog posts.

2) Gallbladder surgery can make weight loss incredibly difficult.  I have two very popular blog posts on what post cholecystectomy patients need to do to lose weight.  Supplementation is absolutely KEY to helping them balance the nutritional deficits caused by their surgery.  I have very specific recommendations for anyone who has had their gallbladder removed.

3) Bariatric Surgery is a double edged sword – it can be a life saver, or it can leave people feeling more frustrated than ever.  Bariatric patients all have altered digestion and at some point or another they all experience nutritional deficits.  An optimal body is a balanced body, therefore, bariatric patients need to be much more diligent about their diet and they should strive to supplement their diet with liquid-based dietary supplements whenever possible to ensure optimal absorption.

4) Consider getting ELISA (blood test) to determine your allergies and sensitivities.  Then you can take the guess work out of what substances are causing you inflammation and you will know exactly which ones to remove or limit from your diet.  ALCAT or ALLETESS are two that I use in my office.

 

Success steps: 

  • Start by taking before pictures – take a face view and a full body view. Clothed is just fine because that is how the world sees you!
  • Take your measurements, write them down and stick them aside.
  • Write down your goals!  This is important — remember the adage, “Write it down & make it happen”?  People that write down their goals are significantly MORE likely to achieve them than those who just dream about them.
  • Don’t let a bad day get you down.  A momentary lapse doesn’t mean you have to abandon your diet and health goals.  It isn’t about being PERFECT, it is about doing the BEST YOU CAN!
  • When you weigh yourself, weigh yourself first thing in the morning after going to the bathroom.  As a rule, I do not recommend weighing every day, but rather every week.  It is completely normal for women’s weight to fluctuate by 1-4 pounds per day.  What you eat, drink, and your physical activity all contribute towards this.  it is not uncommon for some people, particularly those with autoimmune conditions like Rheumatoid Arthritis or Hypothyroidism to fluctuate by more than 5 pounds a day when they are particularly inflamed.
  • Focus on how your clothes fit and how you feel – that is a better indicator of your momentum and success than a number on the scale.
  • visit https://www.facebook.com/groups/Weightlossresources for help and support.

 

 

1. McCulley, DeWayne. Death to Diabetes. North Charleston: BookSurge LLC.© 2005
2. Ketogenic Diet Improves Insulin Sensitivity and Numerous Aging Markers. Retrieved April 26, 2014 from: http://articles.mercola.com/sites/articles/archive/2014/02/02/ketogenic-diet-health-benefits.aspx
3. ibid
4. Hyman, Mark. The Blood Sugar Solution. NY: Little, Brown and Company. ©2012
5. McCulley, DeWayne. Death to Diabetes.
6. Sweet taste signaling. Retrieved April 26, 2014: http://www.qiagen.com/products/genes%20and%20pathways/pathway%20details.aspx?pwid=425
7. How inflammation makes you fat and diabetic (and vice versa).
http://chriskresser.com/how-inflammation-makes-you-fat-and-diabetic-and-vice-
8. ibid
9. ibid
10. Obesity makes fat cells act like they are infected. Retrieved April 26, 2014: http://www.sciencedaily.com/releases/2013/03/130305145145.
11. ibid
12. Proteolytic enzymes among top 10 ways to help decrease inflammation. Retrieved April 26, 2014: http://www.enzymesinc.com/index.php?id=
13. Quell the fire of Inflammation the immense power of proteolytic enzyme therapy. Retrieved April 26, 2014: http://metabolichealing.com/quell-the-fire-of-inflammation-the-immense-power-of-proteolytic-enzyme-therapy/
14. ibid
15. Bromelain. Retrieved April 26, 2014 : http://www.webmd.com/vitamins-supplements/ingredientmono-1089-BROMELAIN.aspx?activeIngredientId=1089&activeIngredientName=BROMELAIN
16. The Microbes in Your Gut May be Making You Fat. Retrieved April 29, 2014: http://www.livescience.com/41954-gut-microbes-make-you-fat.html
17. ibid
18. Certain probiotics could help women lose weight, study finds. Retrieved April 30, 2014:
http://www.sciencedaily.com/releases/2014/01/140128103537.htm
19. Why Use Probiotics For Candida? Retrieved Apriil 30, 2014: http://www.thecandidadiet.com/probiotics.htm

 

 

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Disclaimer: Consult your physician before beginning any diet or exercise program. Dr. Miranda’s protocol is offered as generalized information and should not be construed as medical advice.
Copyright (c) 2014, 2015 Miranda Jorgenson. All rights reserved. This material may not be published, broadcast, rewritten or redistributed in whole or part without the express written permission of the author

Have you hit a weight loss plateau?  TruElevate can help you bust through it!

Have you hit a weight loss plateau? TruElevate can help you bust through it!

It has been a long time since I have done a product specific post, but I am so excited about the release of this product next week, that I just had to tell you about it…

TruElevateThe latest creation from TruVision Health, TruElevate is a synergistic blend of ingredients known to promote healthy weight loss.  In fact, TruElevate was designed to help individuals with resistant fat break through their weight loss plateaus. Furthermore, it comes in two unique versions – a delicious chocolate smoothie, or as easy-to-swallow capsules.  So how does it work?  In a nutshell, TruElevate acts to decrease appetite, balance glucose and insulin levels, burn fat (with an emphasis on stubborn abdominal fat), and provide you with gentle, sustained energy so that you can get out and enjoy life more!  While it aids in fat loss, it doesn’t do so at the cost of losing muscle.  It helps you to maintain your muscle mass and feel good while doing it.  It contains several ingredients that have balancing or reparative properties to ensure you have ‘healthy’ weight loss.  If you’ve been stuck in a rut – then give TruElevate a try!

Here is how each ingredient works:

Ribose – Is a pentose monosaccharide (simple sugar) which forms the backbone of RNA and plays roles in metabolism and energy (ATP) production.  Early research indicates that taking ribose supplements orally may improve energy, sleep, the sense of well-being.  Studies also show that it supports healthy heart function, a reduction in fatigue, restless leg syndrome, and may lessen symptoms associated with fibromyalgia . Ribose may lower blood sugar levels, so people taking insulin or other diabetic medications should monitor their blood sugar and consult with their physician.1

Inulin – A polysaccharide and functional fiber which acts as a prebioticPrebiotics are substances which support the growth of healthy intestinal flora and probiotics  (good bacteria) in the gut. In dietary supplements, inulin is most commonly derived from the chicory plant.  Studies have  demonstrated that inulin is beneficial in supporting healthy  blood lipid levels, including cholesterol and triglyceride levels.  It promotes bowel regularity, weight loss, and can also be used as a food additive to improve taste.2

Caffeine – is a natural CNS stimulant which is found in tea, coffee, chocolate, colas, and many other products.  It is commonly used to reduce fatigue and increase mental alertness.  Used in moderation, caffeine can enhance the action of other medications and supplements, and is widely recognized as being safe when used as directed.3

Yerba Mate – a tea derived from the evergreen bush ilex paraguariensis, and has been used for centuries to provide energy and improve concentration.  It has been demonstrated to promote normal blood levels of glucose and cholesterol.  Studies also indicate it may be beneficial for urinary tract health, colon health, bone density, healthy mood, and weight loss.  Consumers of Yerba mate report that it provides them with the energy and alertness of caffeine without any ‘jitters’ or sleep disturbances.4,5

N-Acetyl Tyrosine – An amino acid that may be difficult for the body to make in optimal concentrations. It is used as a building block to make new proteins and cells,  and to aid the recovery and repair of muscles and other systems.  One of its key roles is that it aids in the synthesis of dopamine – one of our main neurotransmitters.  Dopamine is directly correlated to your emotional responses, behavioral responses, and addictions.    Dopamine levels are also associated with norepinephrine  – a neurotransmitte related to adrenalin.  Maintaining healthy dopamine levels results in stress alleviation, enhanced mood, and improved energy and concentration.6

Taurine – A sulphur-bearing amino acid that is a required building block for proteins.  Certain tissues of the body have higher concentrations and  requirements  including the heart, brain, muscles, and blood cells.  It has been used to support healthy cardiovascular function, blood pressure, blood lipid profiles, and as an agent of repair for those with oxidative damage from diabetes and alcoholism.7,8  It also helps the body respond to mental and physical forms of stress.

Phenylethylamine – is a natural chemical found in the body which boosts mood, mental drive, concentration, productivity, and aids in fat burning.  It is also one of the components in chocolate that makes it so appealing.9

Green Tea – Used for centuries a daily tonic and all-purpose beverage, green tea is an extract form the Camellia sinensis plant.  Studies have demonstrated that green tea extracts have thermogenic properties, and can reduce body mass index (BMI) and obesity levels (particularly abdominal fat).10,11

Evodiamine – An Asian plant extract that has been demonstrated in laboratory studies to reduce both fat uptake, act as a thermogenic, and stimulate metabolism.12,13

Trimethylglycine – An organic compound found in many plants, but commonly isolated from beets.  Trimethylglycine is required for methylation, and for the synthesis of neurotransmitters.  It also plays a key role in energy production, and is beneficial for optimal digestion, liver health, and certain detoxification pathways.14,15

Theacrine –  is a natural plant extract which structurally resembles caffeine but appears to have fewer side effects, making it known as an acceptable alternative to caffeine.  It is noted to increase energy levels, and has stimulatory effects.  It may boost physical activity, motivation, concentration, and levels of alertness.  Anecdotal reports suggest it may be useful in reducing fatigue, and have anti-aging and immune boosting properties.16,17

Glucomannan – Often found in the cell walls of certain plants, Glucomannan is a polysaccharide/dietary fiber.  It has been used as a food additive to emulsify fats and act as a thickening agent.  As a dietary supplement, it can decrease appetite and it slows the absorption of sugars and fats in the gut;  which can help to balance glucose levels, and result in weight loss.  As the fiber passes through the intestinal tract, it absorbs water, which also helps glucomannan improve bowel health and regularity. 18,19

Huperzine –  purified extract from Chinese Club Moss.  It is associates with improved memory, mental focus and clarity, muscle function, energy use, and sleep.20

DHEA – Is a hormone (dehydroepiandrosterone) naturally produced in the body, however both stress and age decrease its production and many people turn to dietary supplementation to maintain optimal levels.  DHEA has been associated with enhancing immune function, energy production, normalizing hormones, building and maintaining muscle, bone health, and balanced mood. It is believed to have anti-aging benefits and plays a role in weight loss; particularly in the reduction of abdominal fat and insulin sensitivity.  Lower levels of DHEA are found in people with chronic health conditions, including diabetics, and those with cardiovascular dysfunction, inflammatory disorders, immune disorders, and with those taking certain medications – including corticosteroids and hormonal birth control.21,22,23

Xylitol – a natural sugar alcohol commonly extracted from birch trees for the dietary supplement market.  It is used in lieu of sugar in “sugar-free” products, and is believed to prevent dental cavities and ear infections when taken orally. It is considered a ‘diabetic friendly’ sweetener.24

Available soon: You will be able to get TruElevate as part of our convenient Combo-Packs

Available soon: You will be able to get TruElevate as part of our convenient Combo-Packs

**A note on resources – while I had the option to use any of a variety of available sources for the information contained above, I chose to stick to popular and widely accepted sites such as WebMD and the MayoClinic.  Whenever possible, I did not use sites associated with the manufacture or sale of dietary supplements so there would be no accusations of ulterior motivation. These resources are not all encompassing, but are user friendly, and I encourage you to be your own informed consumer and do your own fact checking.

  1. http://www.webmd.com/vitamins-supplements/ingredientmono-827-ribose.aspx?activeingredientid=827&activeingredientname=ribose
  2. http://www.webmd.com/vitamins-supplements/ingredientmono-1048-inulin.aspx?activeingredientid=1048&activeingredientname=inulin
  3. http://www.webmd.com/vitamins-supplements/ingredientmono-979-caffeine.aspx?activeingredientid=979&activeingredientname=caffeine
  4. http://www.drweil.com/drw/u/QAA401108/Is-Yerba-Mate-Tea-Healthy.html
  5. http://www.webmd.com/vitamins-supplements/ingredientmono-828-mate.aspx?activeingredientid=828&activeingredientname=mate
  6. http://nootriment.com/n-acetyl-l-tyrosine/
  7. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586397/
  8. http://www.webmd.com/vitamins-supplements/ingredientmono-1024-taurine.aspx?activeingredientid=1024&activeingredientname=taurine
  9. http://nootriment.com/phenylethylamine/
  10. http://www.nlm.nih.gov/medlineplus/druginfo/natural/960.html
  11. http://news.psu.edu/story/310179/2014/04/02/research/research-suggests-green-tea-exercise-boost-weight-loss-health
  12. http://www.webmd.com/vitamins-supplements/ingredientmono-1159-evodiamine%20(evodia).aspx?activeingredientid=1159&activeingredientname=evodiamine%20(evodia)
  13. http://www.ncbi.nlm.nih.gov/pubmed/11582540
  14. http://www.ncbi.nlm.nih.gov/pubmed/20108209
  15. http://www.uofmhealth.org/health-library/hn-2807004
  16. http://www.webmd.com/vitamins-supplements/ingredientmono-1280-theacrine.aspx?activeingredientid=1280&activeingredientname=theacrine
  17. http://www.nootropicmind.com/theacrine-a-future-alternative-to-caffeine/
  18. http://www.webmd.com/vitamins-supplements/ingredientmono-205-glucomannan.aspx?activeingredientid=205&activeingredientname=glucomannan
  19. http://www.ncbi.nlm.nih.gov/pubmed/6096282
  20. http://www.webmd.com/vitamins-supplements/ingredientmono-764-huperzine%20a.aspx?activeingredientid=764&activeingredientname=huperzine%20a
  21. http://www.mayoclinic.org/drugs-supplements/dhea/background/hrb-20059173
  22. http://www.webmd.com/diet/dhea-supplements
  23. http://www.nlm.nih.gov/medlineplus/druginfo/natural/331.html
  24. http://www.webmd.com/vitamins-supplements/ingredientmono-996-xylitol.aspx?activeingredientid=996&activeingredientname=xylitol

 

©2015, Miranda Jorgenson.  May not be used in whole or in part without the expressed written permission of the author.

 

These statements have not been evaluated by the Food and Drug Administration.  These products are not intended to diagnose, treat, cure, or prevent any disease.

How can I be losing fat if my weight stays the same?

How can I be losing fat if my weight stays the same?

This is an aspect of weight loss that perplexes a lot of people – they start a new diet and notice their clothes getting looser, or their face getting thinner – but their weight is staying the exact same!  It is frustrating, because you *think* your diet is working but you step on the scale and feel like a big old failure.

Well, I am here to tell you that you can relax!  You are not a failure!  You are experiencing the wonders of the fat cell in action (I can hear you saying, “big whoop — skinny thighs are what excites me!”).

Let’s start off with a little physiology lesson.  In your body you have 10-30 billion fat cells, and that is if you are of a healthy weight.  Overweight people can have 75 billion fat cells or more, and it is not unheard of for morbidly obese people to have 250-300 billion fat cells overwhelming their boney frames!  That is a LOT of fat cells (adipocytes). Picture each fat cell like a little deflated balloon.  That balloon can be relatively empty or filled to the brim and be stretched over 10x its normal size.  Now these fat cells are stubborn creatures – you can always make more, but once you have them, they are yours for good.    Up until very recently1, it was thought that the only way to get rid of fat cells was to cut them out, but you can deflate them — and this is the key to losing weight effectively.

fatcell

You see, fat cells are little storage tanks, and despite your most heartfelt desires to the contrary, they are remarkably efficient at storing fat in the form of triglycerides within the cell.  When we want to burn fat – it isn’t an easy matter of having your brain tell your body, “we need more energy – let’s burn that  love handle”. It doesn’t work that way!   We need two enzymes, hormone sensitive lipase and adipose glyceride lipase to break down the triglyceride within fat cell where it is then released into the bloodstream as FFA’s.  The more blood supply an area has, the better it can whisk away those FFA’s that are getting dumped from the fat cells.  You can see this on your own body — take a second and poke your facial cheeks.  See, the fat there is nice and soft because it has a good blood supply.  Now grab the fat on your belly or on your butt.  Feel the difference?  It is dense and hard.  It doesn’t have a good blood supply to whisk fat away.  This is why when you start losing weight, it usually leave the ‘soft’ places first – your face, breasts, and arms and leaves you feeling like a saggy humpty dumpty for a while.  This blood flow issue also leads us to our key point – when you start a diet and are burning fat, the scale often stays immobile despite you noticing that you are shrinking.  This happens because the body abhors a vacuum.  When the adipocytes dump out their fatty contents, your body doesn’t like to see an empty cell – so it shuttles water into the cell to fill up the space the fat just occupied.  This is also why fat loss can be considered an inflammatory process and why you often feel bad, tired, sick, or swollen when you are dieting (there are other chemical factors, but we will discuss those at another time).  Your body is literally replacing the fat with water!  This process is more extreme for some people than for others, and some fortunate souls experience very little of this water replacement.   This is also why your stomach or thighs can feel mushy or spongy when you are losing weight – you are replacing a dense fat with water.

 

So, what you can do, especially if you know that you have resilient fat or are a water hoarder?  Well, there are a few simple things:

  1. Stay hydrated. I know, you’re thinking, “Why put more water into a swollen body?”,  — Well, you need to flush out the metabolites from breaking down those FFA’s.
  2. Limit Caffeine and Alcohol. A little of either substance is OK, and small doses of caffeine can even be beneficial because it has a mild diuretic effect.  Large amounts of either (and by large I am referring to more than 3 caffeinated beverages or more than 1 glass of wine or beer each day) can cause you to swell up like a balloon at the Macy’s Day Parade AND make your hard-earned weight loss come to a grinding halt.
  3. Shake your booty. Yes, I said it.  The largest lymphatic pump in your body is the quadriceps muscles in your legs, so anything that gets those quads pumping — like walking, dancing, or biking, increases your lymph flow and your blood flow.  If you work yourself up to a decent exertion point, then you will really increase systemic blood flow, and breathing (and breathing is the means by which your body excretes the metabolites of burnt fat cells!).  Dig out those Richard Simmons’ shorts you’ve been hanging onto for the past 20 years — (they are back in style)  and get ‘Sweatin’ to the Oldies!’

So there you have it!  Know that you are not hallucinating – your face is thinner, your breasts are shrinking, and those bingo wings are real.  Your scale just hasn’t caught up with your body!  The more you follow the above steps – the faster you will purge that excess water (and inflammation) and the scale will start moving in the right direction.

 

 

1.http://www.nytimes.com/2008/05/05/health/research/05fat.html?_r=0

Dr. Miranda’s Plateau Busting Protocol

Dr. Miranda’s Plateau Busting Protocol

Dr. Miranda’s Plateau Busting Protocol™

My Plateau Busting protocol is a work in progress, as we discover new information in the literature – we tweak this as needed.  By popular demand, I have enclosed the original protocol  here so people can refer to it, but please know that this protocol works for many people but I am currently putting the final touches on my weight loss book which will have many more options for people.

 

plateaubusting3

 

One of my most popular videos on Youtube is “What To Do When Your Hit a Weight Loss Plateau”, and due to it, and the popularity of my Facebook group  www.facebook.com/WeightLossResources one of the most common things reported to me is that people are hitting plateaus and are at a loss as how to proceed since they have tried everything but they just can’t seem to break through that scale barrier. So, in my quest to help my team members and friends, I got out my pharmacology texts and my physiology texts and took a long, hard look at things to try to figure out how we could best use  certain products to blast through those stubborn weight plateaus and barriers.
After studying these texts and the physiology behind how certain organ systems and pathways work – I had a brainstorm on how to dramatically increase weight loss using a few small dietary changes and chronopharmacology; the study of how biological rhythms interact with metabolism and medication & nutrient absorption. So to put my theory to test, I asked for a spectrum of volunteers from my online groups. I laid out the rules for the trial, and all participants had to have been stuck at a weight loss plateau (or actually gaining weight) for a minimum of a month. It ended up that nearly every participant had been at a plateau for 3-6 months or longer. So we were dealing with some bodies that were very resistant to weight loss. Let me be clear, this was a trial to test a theory. It was not a double-blind clinical study which is virtually impossible to run in the real world because you cannot control or modulate people’s individual diets and lifestyles to the extent that would give you enough controls to have a true clinical objectionable study. My trial centered on three products: a glucose regulating product,  a proteolytic enzyme formula, and a potent probiotic.  The participants were instructed to continue taking any medications that had been prescribed to them and to continue taking any supplements they had been taking with the exception of any ‘weight loss’ products. I issued 5 STEPS that they were to follow:

  • 1) STEP 1 – Ketogenic or “Death to Diabetes®” breakfast comprising of a cup of coffee or tea (if desired) and one of 2 approved breakfasts
  • 2) STEP 2 – Taking 2 capsules of TruFix (from TruVision Health) per day.  An optional step is to drink a glass of Tru Heart & Hydration at this time.
  • 3) STEP 3 – Taking Biotics Research Intenzyme Forte ™ twice daily on an empty stomach
  • 4) STEP 4 – Taking 1-2 capsules of an approved probiotic  at bedtime, on an empty stomach
  • 5) STEP 5 – Twice daily, or more –  drinking a cup+ of tea from the approved list of teas.

Other than that, they were to eat regular meals and to be mindful about excessive carbohydrate intake. They were to continue life as usual. They were instructed NOT to start an exercise program if they hadn’t already been doing it.. We tried to minimize the affect ancillary factors would have on the protocol.

“It’s been barely been over 2 weeks and I’m down 10 lbs with my… products and with just a few changes to what I was already doing!”   Trial Participant

So now you know the basic steps, but you need to understand the science and rationale behind the recommendations:

STEP 1

Upon waking you are allowed to eat the following:
1) 1 cup of coffee or tea ( if you drink coffee or tea) * “Bulletproof Coffee” is acceptable (1 tbsp of organic grass-fed butter blended into your coffee with or without added coconut oil)
2) Only protein for breakfast – eggs, fish, steak, bacon, sausage, left-over meat from the previous night’s dinner. 2-4 oz of protein is fine. The only other acceptable breakfast is the “Death to Diabetes©”1 breakfast – consisting of 3-4 oz of meat or fish along with up to 2 cups of steamed green vegetables dressed with 1 tbsp of olive oil, 2 tbsp of vinegar, and any type of Mrs. Dash™ seasoning. The latter breakfast is better for people who prefer to eat larger meals early in the day.
3) Healthy fats – 1 tbsp of coconut oil, grass-pastured butter, avocado, or raw nuts (raw walnuts, pecans and macadamia nuts are particularly beneficial) may be added to control hunger or cravings.

Rationale: The breakfast needs to be essentially carb-free. Do not ask me if you can have fruit, or yogurt, or cereal, or pancakes, or donuts, or oatmeal, or cheese, or anything else. We want ONLY protein so we are starting off the day by leveling glucose and insulin. Those other foods, even if they are ‘healthy’ choices, will spike your glucose and insulin, and then your TruFix has to work twice as hard to be effective. This is, in effect, a ketogenic or paleo-style breakfast. This type of meal “shifts the body’s metabolic engine from burning carbohydrates to burning fats”2 and improves insulin sensitivity and leptin resistance3. Consuming carbohydrates, even in healthy forms such as those from fruit (fructose) or dairy (lactose) causes surges in blood glucose levels which in turn initiate the release of insulin. People with excess weight have been shown to be insulin resistant4 and therefore if we by pass this, we set the stage for less severe glucose and insulin fluctuations throughout the day. In fact, in his book Death to Diabetes™, researcher DeWayne McCauley postulates that eating a paleo or ketogenic breakfast is the most important factor in modulating glucose levels throughout the day.5

STEP 2


1) Take 2 capsules of TruFix each morning.  

Rationale: There are several. First, we want to regulate glucose and insulin spikes.  Even as little of five extra pounds of body weight indicates some degree of insulin resistance.  One, we are consumingthe TruFix  at  or near the same time the same time as protein. Protein takes longer to digest than carbohydrates and the stomach retains protein containing meals for longer periods of time before it is sent through to the small intestine. This enhances absorption of the TruFix ingredients. Two, for those doing the optional step of drinking the TruHeart & Hydration drink mix,  there is a well established neural-lingual connection between your taste buds and the brain. Primary gustatory fibers synapse centrally in the medulla, so upon consuming sweet substances, the sweet taste receptors in the mouth stimulates the release of dopamine in the brain. We can use this signaling to turn down the body’s desire for carbohydrate-rich or sweet substances; “…sweet taste is modified by circulating hormones. Recently, the effect of leptin on sweet-responding taste cells has generated much interest. Leptin, a protein hormone secreted mainly by adipocytes regulates body mass and suppresses insulin secretion by the activation of ATP-sensitive KCn . Its inhibitory effect on TRCs also involves the activation of a K+ conductance and membrane hyper polarization. Thereby the hormone partially blunts nerve signals indicating sweet taste, which, presumably, makes food less attractive.”6 So, in effect by concentrating the sweetness of Heart & Hydration, and holding it for a slightly prolonged period in the mouth to extend its contact time with taste buds, we are fooling the brain into believing that it has consumed a significant amount of carbohydrates, and it turns down your appetite and cravings for them.

The first few days of trying this new method seemed *very sweet* to me, but as I persevered, I noticed a marked reduction in both my appetite and cravings, as did the trial participants. In order for this neural-lingual activation to work you must be tasting the Heart & Hydration. Do not drink it with a straw, do not use ice (which has a numbing effect on the taste buds), do not cut it with cranberry juice, Mio™ Drops, or any other agent that will alter the taste.

 

STEP 3 –

1) Mid-morning and mid-afternoon take Intenzyme Forte™ . The trial was performed using 1 capsule of  Intenzyme Forte  mid-morning, and 1 capsule mid-afternoon on an empty stomach. Empty stomach usually means 30 minutes+ prior to eating or a minimum of 90 minutes after eating. *This HAS to be taken on an empty stomach or IT WILL NOT WORK! Please note, if you have significant levels of inflammation, you can take 2 capsules twice a day, but for simplicity and to curtail costs, the trial was performed using 1 capsule twice daily.

Rationale: Where do we start? There are so many! First, let’s take a look at how inflammation makes you fat : Inflammation begins within the fat cells themselves. Most people think of inflammation and assume that means joint pain, but inflammation is so much more. At its very core a fat cell is an inflamed cell. “As glucose is moved into fat cells, they produce an excess of Reactive Oxygen Species (ROS) which in turn initiates an inflammatory cascade within the cell”7. As the percentage of body fat increases, the rate of inflammation increases exponentially. This inflammation causes insulin resistance, and can be noted with C-Reactive Protein testing. The inflammatory cascade eventually makes its way to the brain, specifically the hypothalamus, where it causes leptin resistance.8 Leptin is your ‘hunger’ hormone and is noted for controlling your appetite and regulating your metabolism. The more fat you have the greater potential you have for leptin resistance, which affects your glucose regulation, and slows your metabolism which results in more weight gain and insulin resistance. It is a vicious cycle that keeps getting progressively worse. Inflammation within the gut itself, where 80% of immune function resides, further causes both leptin and insulin resistance. An imbalance in the gram-negative bacteria in the gut has been shown to produce an endotoxin called lipopolysaccharide (LPS) and a cytokine cascade which causes inflammation, insulin resistance, and weight gain.9 But I digress, we will get into how bacteria are related to obesity in the next step. Obesity makes fat cells act like they are infected.10 The stimulation of fat cells by excess calories causes the cells to make Major Histocompatibility Complex II (MHCII), which in turn sends your immune system into over-drive, mimicking autoimmune dysfunction.11 This breakthrough in understanding the fat cell may prove to be crucial future weight loss and aging studies.

Intenzyme Forte™ is a proteolytic enzyme formula. When taken on an empty stomach, it can be absorbed intact into the bloodstream12 where it can be directed towards breaking down those inflammatory products in the body. Proteolytic enzymes have been demonstrated to reduce Tumor Necrosis Factor alpha (TNF-a), a cytokine protein that signals inflammatory responses along with other pro-inflammatory mediators such as Prostaglandin E2 and Thromboxanes.13 Autoimmune dysfunction is associated with increased levels of TNF-a.14

In addition to the overwhelming capacity of proteolytic enzymes to interrupt this fat-inflammation cycle, certain ones, including bromelain, have a secondary action of helping the body to utilize insulin more efficiently which in turn helps to keep blood glucose fluctuations less dramatic. 15

To summarize all of this technical jargon : fat cells are inflamed cells. Think of each fat cell like a little water balloon filled with fat. The fat creates chemicals which not only irritate the body, but stimulate the body to keep making more and more fat cells. This is very stressful on the body which finds the inflammatory chemicals hugely irritating, so the body tries to dilute those irritants by sending more water to the area (bloating and swelling) to flush those chemicals away. This not only sends the body down the pathway to blood sugar dysregulation and even diabetes, but can result in premature aging and even autoimmune-type degeneration. Once you have made a fat cell, you can never get rid of them (barring surgery like liposuction) but you can deflate those ‘balloons’ of fat, and turn off the inflammation production. That is what we are trying to achieve with this step.

” I started Plexus on May 24, 2013. I did exceptionally well with weight loss and then November hit. I got stuck. As the weeks passed I saw my numbers going back UP. I tried everything… Nothing was working NOTHING – and no one seemed to have any answers for me except the usual drink your water, what are you eating, did you do the spit test….I just did my 3 week weighs and measurement since I started Dr Miranda’s way of taking my… products…. apparently my inches are on super movement (and keep in mind my weight loss would probably have been more BUT I had a huge “bad” Easter dinner and we hit and all you can eat wing night in this time period!)

So I am back to not having to starve to death and the scales are moving in the right directions!!! In just 2 weeks, I have lost 7.5 inches and 5.3 lbs.

WAHOOOOOOOO! ”  Trial participant

 

STEP 4 –

1 ) At bed time, take 1-2 capsules of a broad spectrum probiotic. Again you want to take your probiotics on an empty stomach so it gets passed through your stomach acid quickly and so it can colonize in your large intestine while you have your longest period of bowel rest. If you take magnesium, this is an ideal time to take it too.

Rationale: An increasing body of evidence suggests that obesity is directly linked to the bacteria in your gut. In fact the bacteria in thin people differs from the bacteria in overweight people. 16 Thin people and overweight people have entirely different strains and ratios of intestinal flora.17 Researchers at Laval University in Canada, found that female test subjects receiving probiotics lost twice as many pounds as those in the placebo group over the course of a twelve week period.18 Furthermore, probiotics may normalize intestinal pH, making it more difficult for candida albicans to thrive, and may crowd out pathogenic bacteria sepcies.19 There are variations of professional opinion on the best way to consume probiotics, but heat and acid are enemies of bacteria, so if you can get the probiotics through the stomach acid as quickly as possible, then you have created optimal conditions for the greatest number of probiotics to survive. Hence the need to take them on an empty stomach. Taking them at night coincides with the greatest period of bowel rest for most individuals, which allows for longer periods of contact between the probiotics and the intestinal mucosa, which may improve the rate of colonization. When you take probiotics with food, they stay in the acidic stomach for much longer, which kills off a greater percentage of the bacteria.

STEP 5 –

1) At some point throughout the day, please consume 2 cups of tea – either hot or cold (make it yourself, do not use premade or commercial preparations) Green tea, Black tea, Dandelion Tea, Yarrow, Rosehip, Cornsilk tea, Roobios, or Pu-Ehr are all acceptable forms. Warm water with the juice of 1 lemon is acceptable as well. Sweeten with stevia or a small amount of table sugar (so its glucose/fructose ratio is balanced) to taste if needed. Mix up these forms of tea. If you use only one type, your body will accommodate, and we will lose the reason why we are adding this to the program. You don’t have to use all of them, but experiment and try at least 2 or 3. You can drink 2 cups at once or drink 1 cup at two different times.

Rationale: All of these teas have a known mild diuretic effect and by keeping them in rotation our body will not accommodate to it- thereby it maintains its effectiveness. Geranax had potent diuretic properties, and this contributed to the immediate weight loss many people experienced when they took it initially. As we already discussed, the body likes to flood inflamed tissues with excess water, so if we drink tea, its mild, natural diuretic properties help us flush those inflammatory by-products from the body, and that will support healthy weight loss. Please note: many of the teas listed, particularly the herbal teas are naturally caffeine-free. Should you choose to use green tea or black tea however, it is the caffeine portion of it which acts like a diuretic, so make sure to purchase regular versions and not decaffeinated ones.

 

Now for the rest of the questions you might have:

  • Meals – Make healthy choices when you can. If you can eat lower amounts of carbohydrates, you should see results faster. Try to eat GOD made foods and avoid as many Man-made foods as possible. *Perfect meals are meat & veggies*
  • If you drink alcohol, limit yourself to one (1) oz of hard liquor or 1 6(oz) glass of wine per day. If you drink more than this, it increases the difficulty you will have losing weight tremendously.
  • Avoid artificial sweeteners
  • Keep your fruits and yogurts as side dishes to your meals – like dessert.
  • If you already exercise, keep continuing what you are doing. Please don’t start a new program at the same time you initiate a new diet. You want to know what is working for you and what isn’t.
  • If you are consuming the beverages as described, please make sure that you are drinking your water. These cups of tea do count towards your daily quota.
  • Please do not skip meals.

We are going to do a few things differently than what you have been doing. Please follow these instructions:

** Start by taking your measurements and writing them down.   When you weigh yourself, do it first thing in the morning after you have gone to the bathroom. Do not wait until after you have eaten, and do not weight yourself later in the day. If you are measuring your blood sugar, please record your average fasting glucose and post-prandial reading (if you track that one. Take photos of yourself if you would like. You always want to weight yourself and take our measurements at the same approximate time of the day**

  1. STEP 1 – Ketogenic or “Death to Diabetes®” breakfast comprising of a cup of coffee or tea (if desired) and one of 2 approved protein based breakfasts
  2.  STEP 2 – TruFix™ , 2 capsules per morning.  Optional — 1 packet of Tru Heart & Hydration mixed into 8-12oz of water and hold it in the mouth for a few seconds before swallowing
  3.  STEP 3 – Take Intenzyme Forte™ twice daily on an empty stomach (mid-morning & mid-afternoon)
  4. STEP 4 – Take 1-2 capsules of an approved probiotic at bedtime, on an empty stomach
  5. STEP 5 – Twice daily, drinking a cup+ of tea from the approved list of teas. (Green tea, Black tea, Dandelion Tea, Yarrow, Rosehip, Cornsilk tea, Roobios, or Pu-Ehr, or water with the juice of 1/2 to 1 whole lemon in it)

Helpful pointers: :

  • Meals – Make healthy choices when you can. If you can eat lower amounts of carbohydrates, you should see results faster. Try to eat GOD made foods and avoid as many Man-made foods as possible. *Perfect meals are meat & veggies*
  • If you drink alcohol, limit yourself to one (1) oz of hard liquor or 1 6(oz) glass of wine per day. If you drink more than this, it increases the difficulty you will have losing weight tremendously.
  • Avoid artificial sweeteners
  • Keep your fruits and yogurts as side dishes to your meals – like dessert.
  • If you already exercise, keep continuing what you are doing. Please don’t start a new program at the same time you start a new diet. You want to know what is working and what is not.
  • If you are consuming the beverages as described, please make sure that you are drinking your water. These cups of tea do count towards your daily quota.
  • Please do not skip meals.

visit https://www.facebook.com/groups/Weightlossresources for help and support.

1. McCulley, DeWayne. Death to Diabetes. North Charleston: BookSurge LLC.© 2005
2. Ketogenic Diet Improves Insulin Sensitivity and Numerous Aging Markers. Retrieved April 26, 2014 from: http://articles.mercola.com/sites/articles/archive/2014/02/02/ketogenic-diet-health-benefits.aspx
3. ibid
4. Hyman, Mark. The Blood Sugar Solution. NY: Little, Brown and Company. ©2012
5. McCulley, DeWayne. Death to Diabetes.
6. Sweet taste signaling. Retrieved April 26, 2014: http://www.qiagen.com/products/genes%20and%20pathways/pathway%20details.aspx?pwid=425
7. How inflammation makes you fat and diabetic (and vice versa).
http://chriskresser.com/how-inflammation-makes-you-fat-and-diabetic-and-vice-
8. ibid
9. ibid
10. Obesity makes fat cells act like they are infected. Retrieved April 26, 2014: http://www.sciencedaily.com/releases/2013/03/130305145145.
11. ibid
12. Proteolytic enzymes among top 10 ways to help decrease inflammation. Retrieved April 26, 2014: http://www.enzymesinc.com/index.php?id=
13. Quell the fire of Inflammation the immense power of proteolytic enzyme therapy. Retrieved April 26, 2014: http://metabolichealing.com/quell-the-fire-of-inflammation-the-immense-power-of-proteolytic-enzyme-therapy/
14. ibid
15. Bromelain. Retrieved April 26, 2014 : http://www.webmd.com/vitamins-supplements/ingredientmono-1089-BROMELAIN.aspx?activeIngredientId=1089&activeIngredientName=BROMELAIN
16. The Microbes in Your Gut May be Making You Fat. Retrieved April 29, 2014: http://www.livescience.com/41954-gut-microbes-make-you-fat.html
17. ibid
18. Certain probiotics could help women lose weight, study finds. Retrieved April 30, 2014:
http://www.sciencedaily.com/releases/2014/01/140128103537.htm
19. Why Use Probiotics For Candida? Retrieved Apriil 30, 2014: http://www.thecandidadiet.com/probiotics.htm

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Disclaimer: Consult your physician before beginning any diet or exercise program. Dr. Miranda’s protocol is offered as generalized information and should not be construed as medical advice.
Copyright (c) 2014 Miranda Jorgenson. All rights reserved. This material may not be published, broadcast, rewritten or redistributed in whole or part without the express written permission of the author

I’ve lost all of this weight, so what do I do about my bingo wings?

One of the few negative things about weight loss is that some people are left with focal areas of saggy skin.  Not only is this skin unsightly, but it can create hygiene issues and physical discomfort.  Even minor weight loss can result in lumpy, less resilient skin that is prone to cellulite.  Larger amounts of weight loss can leave some people with excessive amounts of hanging, sagging skin; which can be prone to skin irritation and even infection or chronic inflammation.  Some people find their abdominal skin is so loose that it appears more like an alien landscape than the body they have come to know.  It just doesn’t feel like “you”.

 

It used to be that you had two options on dealing with it – you could live with it or you could get it surgically removed.  Well, I am here to tell you that there is a lot that can be done, and if you are still in process with your weight loss journey, there is even more we can do to minimize those dreaded bingo wings and abdominal aprons (pannus).

 

I remember looking at my own abdomen shortly after my second child was born, and thinking “when did I become a shar pei?”  You can be ecstatic about accomplishing your weight loss goals but feel demoralized every time you look in the mirror.  It is not fun, and has to be the least sexy feeling in the world!  So this is what I did, and this is what I recommend to my patients and clients:

 

Wrinkles and skin folds are cute on babies and dogs.  On us, not so much!2

 

First, never under estimate the power of DRY BRUSHING.  Dry Brushing is a technique involving a dry brush (shocking, I know!) where you make long sweeping passes lightly over your skin.  Always moving towards your lymph nodes and heart.

Arrows indicate the direction of your passes with the dry brush1

 

I recommend that you start with your feet and work up towards your waist, then move to your hands and brush towards your heart, finishing with your neck and torso – also directing all brush strokes towards the heart.  Remember, always use a dry brush, and do this before your shower so you wash off any toxins that you release.  Some people chose to purchase two brushes for this task, one a small brush that straps to the palm of your hand, and the other, a similar brush attached to a stick to make reaching inaccessible areas easier.

 

So how does this work, well, first we need to remember that your skin is your largest organ, and is occasionally referred to as your third kidney because it eliminates approximately a pound of toxins per day, mostly through your sweat glands.  In addition, over 33% of your blood supply is directed to your skin but it is one of the last areas to receive nutrients, so it is subject to showing signs of deficiency.  The skin closely interacts with the lymphatic system, another powerful system of detoxification.

 

ü  Dry brushing stimulates lymphatic drainage and the elimination of toxins

 

ü  It encourages circulation and revascularization of hypoxic tissues

 

ü  By increasing blood flow, it encourages nerve conduction and wound healing

 

ü  It stimulates your immune system

 

ü  It stimulates the production of collagen and elastin, thus tightening skin that has lost some of its elasticity

 

ü  It removes layers of dead skin and encourages the growth of new skin cells

 

ü  It improves skin texture and reduces signs of cellulite

 

ü  It stimulates hormone production and oil gland secretion

 

ü  It helps with more even distribution of fat deposits

 

ü  It improves nervous system functioning by stimulating nerve ending firing and receptors in the skin

 

ü  It is invigorating

 

ü  It is quick and inexpensive

 

Tips – use a light touch on thinner areas of skin, and a stronger touch on thicker areas of skin (like the abdomen, legs, and feet).  It should not hurt, but it should feel invigorating.  Do 8 to 10 strokes on each area before moving on.  When you first get started with dry brushing, you may only be able to tolerate a few minutes of it.  Once established though, it should take 10-15 minutes to cover your entire body.  Do not brush moist skin as you can cause micro tears in the outer layer of skin.  If you can dry brush during your weight loss journey, then you may avoid loose skin all together.  If you have stubborn areas, like under the arms, love handles, or a pannus, – you can spend extra time brushing them to stimulate the skin.  If you have areas that are especially sensitive to the dry brushing, you can avoid them for the time being, the same can be said for damaged or wounded skin.  Never dry brush skin wounds or infections.  Always shower after dry brushing, and if you can end your shower with 15 seconds or so of cold water, that will further stimulate the skin.  I recommend dry brushing 6 days per week, and using a salt or mineral scrub on the 7th day.  This gives your body a break to further detoxify and regenerate.  After your shower, massage a high grade plant oil (olive, coconut, almond, flax, sesame, avocado, castor oil with essential oils, etc.)

 

Other things you can do now to avoid your outer shar pei and encourage skin tightening:

 

1.       Limit sun exposure.  Avoid sunburns and tanning beds.

 

2.       Get a massage.  Massage therapy stimulates circulation, and can release pockets of inflammation.

 

3.       Keep hydrated!  Another reason for you to be drinking that water.

 

4.       Increase your consumption of raw foods.  Raw foods contain enzymes that promote immune function and digestion, and decrease inflammation.

 

5.       Consume high quality protein.  Your body needs high quality protein to replace and repair its own supply.  Collagen and elastin both require protein building blocks.

 

6.       Make sure to wash chlorine from skin after swimming.  Avoid putting chemicals or artificial creams or moisturizers on your skin.

 

7.       Use alcohol in moderation.  Alcohol can severely impact collagen synthesis.

 

8.       Use seaweed or other ‘wraps’ to help tone the skin

 

9.       Take at least 1 Epsom salt bath per week to pull toxins and to increase your serum levels of magnesium (at least 2 cups of Epsom salts in a bath for at least 20 minutes)

 

10.   Use an abdominal or sports wrap on areas you tend to be losing too quickly from so that the skin remains compressed.

 

11.    Avoid cigarette smoke at all cost!

 

 

 

Supplementation

 

Healthy skin requires normal levels of collagen and elastin.  Dry brushing will encourage the production of these, but supplementation is likely necessary. 

 

Vitamin C is the backbone of collagen formation.  500-3000 mg per day is the average daily requirement range.  If you are losing weight quickly or already have lose skin, you will require doses towards the higher end of the spectrum.

 

Magnesium is required for hyaluronic acid production (the gel-like substance that is found in skin, joints, and soft tissue).  It is also required for over 200 different biochemical processes in the body.

 

Omega 3 fatty acids support the fatty membrane structure of all cells and improve skin repair and turn over.

 

Lysine, argenine, glycine, and proline – amino acids necessary for collagen and elastin production.  Glycine also plays a role in blood glucose regulation, muscle repair, digestion, and glutathione production.  You can supplement with these individually or use a broad spectrum amino acid containing supplement like whey protein to get in all of the amino acids.

 

Bone Broth – One of the traditional foods that is rarely found in the modern diet, it has been suggested that a lack of bone broth (and its associated minerals, gelatin, and collagen) is one of the major reasons why arthritis is so prevalent now.  Minerals found in bone broth are highly absorbable, far more than from most dietary supplements.  If you make your own bone broth (which I highly recommend) roast your bones first, then gently boil them with your cut vegetables and 2 tbsp of apple cider vinegar to help make the minerals more absorbable.  You know you’ve made a great bone broth when you refrigerate it and find a thick layer of gel on it.  When you cook meat, try cooking it on the bone for additional collagen and proteoaminoglycans.

 

Green tea – a potent source of catechins, which help with collagen and elastin production.  Enjoy a few cups of green tea each week to reap its benefits.

 

Taking these steps will make a marked improvement in your skin.  Now some people will always be candidates for surgery, but I always recommend using natural methods first, because once you cut, there is no going back.  If you can do these while you are undergoing your weight loss, your skin will tighten at nearly the same rate as your fat loss – thus likely preventing sagginess to begin with.  What do you have to lose other than those bingo wings?!

 

Edited to add:  I’ve had several requests for me to show what a dry brush looks like:  http://www.amazon.com/Tampico-Approx-Inches-Yerba-Prima/dp/B008MONZFI/ref=sr_1_4?s=beauty&ie=UTF8&qid=1386109118&sr=1-4&keywords=skin+brush

 

 

 

 

 

Copyright (c) 2013 Miranda Jorgenson. All rights reserved. This material may not be published, broadcast, rewritten or redistributed in whole or part with out the express written permission of the author. You are welcome to share this link or print this page and use in its entirely.

 

Photo Sources:

 

 

1.  Drybrush picture. Retrieved 12/3/2013 from http://mayamoonhealingarts.com/dry-skin-brushing/

 

2.  Shar pei. Source: imgfave.com via DoanPhuong on Pinterest,   Retrieved 12/3/2012 from http://www.gracielushihtzu.com/baby-shair-pei

 

3. Pannus. Retrieved 12/3/2013 from: http://www.eplasty.com/index.php?option=com_content&view=article&id=627&catid=173:volume-12-eplasty-2012&Itemid=121